Buffalo Bill and Wild Bill Hickok join forces to establish a mail route that can get mail from St. Joseph, Missouri, to Sacramento, California, in ten days. Along the way…

A rich woman and a calculating insurance agent plot to kill her unsuspecting husband after he signs a double indemnity policy.

Drummond manages to save a woman from jumping in front of his car but she runs away with his car. He traces her and she asks him to help her…

A husband and wife detective team takes on the search for a missing inventor and almost get killed for their efforts.